Yes, this is collaborative with research in many other fields as well. As we study the physiology of sleep and it’s impact systemically we are finding an explosion of connections between sleep and many disease states. We are getting closer to having the ability to utilize bio-markers in the diagnosis and treatment of sleep and measuring it’s impact on co-morbid conditions.
In an evolutionary perspective the need for sleep makes no sense, so the association of sleep with various mediators of inflammation, may provide a key insight as to the true function of sleep in the mammalian organism.
In the meantime, the benefits of treating sleep disorders is obvious.
You are very welcome. Glad you found the information interesting.
According to the Centers for Disease Control and Prevention (CDC), heart disease is the leading cause of death among both men and women in the United States. This extremely common and serious health issue is often found in patients suffering from obstructive sleep apnea (OSA), though doctors and researchers are still trying to fully understand the relationship between the two diseases.
What is Cardiovascular Disease?
Cardiovascular disease, commonly known as heart disease, is a general term for general health conditions related to the heart. Most of these conditions are due to arteries that are blocked or narrowed by plaque. Cardiovascular disease is often associated with:
• High blood pressure (hypertension)
• Chest pain
• Abnormal heart rhythms (arrhythmia)
• Heart valve or muscle issues
• Coronary artery disease
• Heart attack
• Heart failure
Heart disease has a myriad of causes and in many cases it is caused by more than one factor. Heart disease can be associated with congenital health problems, lifestyle choices, stress, genetics, and other health issues.
Cardiovascular Disease & Sleep Apnea
Patients with sleep apnea are more likely to be diagnosed with heart disease and patients with heart disease are more likely to be diagnosed with sleep apnea. However, because both sleep apnea and cardiovascular disease often co-exist with other health issues, it is difficult to understand their exact relationship.
Currently, researchers believe that not breathing regularly during sleep results in less oxygen in the blood. This lack of oxygen increases your blood pressure so that oxygenated blood flow to the heart and brain continues. The chronic increase in blood pressure creates heart disease.
In addition, though, heart disease and sleep apnea may often be found together in the same patient because both health issues are more common in men, in the obese, and in an older population.
OSA and Heart Disease Facts
• A Mayo Clinic study found that sleep apnea increases the chance of having a heart attack during sleep.
• According to a study conducted by Boston University School of Medicine, middle-aged men with OSA are 58 percent more likely to receive a heart disease diagnosis over an eight-year period.
• According to the same study, older men with severe sleep apnea were 68 percent more likely to develop coronary heart disease than those with mild or moderate sleep apnea.
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Research has shown that obstructive sleep apnea (OSA) has been linked with heart disease, stroke, diabetes, and a myriad of other serious illnesses, diseases, and health conditions. However, when we talk with many of our sleep apnea patients, their lives are most affected by sleep apnea in a different and simpler way: the sleep disorder robs them of their sleep and, in doing so, robs them of happy, productive, and alert days.
Some of the most commonly reported symptoms of obstructive sleep apnea include:
excessive daytime sleepiness
chronic and extreme fatigue
lack of energy
slow reaction times
the inability to stay awake during tasks
The Serious Issue of Excessive Daytime Sleepiness
• excessive daytime sleepiness
• chronic and extreme fatigue
• lack of energy
• difficulty concentrating
• memory issues
• slow reaction times
• brain fog
• the inability to stay awake during tasks
The Serious Issue of Excessive Daytime Sleepiness
Excessive daytime sleepiness (EDS) is far more grave than just feeling drowsy or run down every now and then. Related to narcolepsy, EDS is a deeply felt, ongoing, and sometimes uncontrollable need to sleep during the day. Sufferers may feel relentlessly tired, fall asleep during tasks, and have trouble remembering what they’ve done or what they need to do. In many cases, EDS is caused by other sleep disorders, such as insomnia or sleep apnea.
EDS often has a devastating effect on patients, especially after months or years of suffering from the problem. Daytime drowsiness and brain fog can significantly lower the quality of your life, from your career to your relationships to your physical safety. Those suffering from EDS may report:
• Not waking up feeling rested or refreshed.
• Falling asleep at critical times, such as behind the wheel of a vehicle.
• Not being able to correctly complete tasks at work due to drowsiness.
• Falling asleep during daily activities, such as eating a meal.
• Not being able to engage in conversations or interactions due to drowsiness.
• Requiring a nap or multiple naps during the day in order to properly function.
• Having difficulty recalling what you have just done or said.
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Two recent studies have linked obstructive sleep apnea and osteoporosis, adding yet another serious disease to the already lengthy list of health problems associated with the nighttime sleep disorder.
In the first sleep apnea study (http://www.ncbi.nlm.nih.gov/pubmed/24735427), conducted by the Chi Mei Medical Center in Tainan, Taiwan, and published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM) in 2014, researchers found that those with obstructive sleep apnea (OSA) had a 2.7 percent higher chance of suffering from osteoporosis and early bone loss than those who did not present symptoms of sleep apnea.
The Taiwan study random samples from 1 million people who are tracked through the country’s National Health Insurance database, focusing on 1,377 patients with newly-diagnosed OSA between 200 and 2008 as well as 20,655 patients who had not been diagnosed with OSA. The study corrected for age, gender, diabetes, hypertension, coronary artery disease, obesity, stroke, hyperlipidemia, chronic kidney disease, gout, monthly income, and geographical location.
In the second sleep apnea study (http://www.sciencedaily.com/releases/2015/02/150203104104.htm), researchers at Oregon Health and Science University in Portland examined how sleep apnea affected bone metabolism. The study, which was published in the Journal of Bone and Mineral Research this year, concluded that chronic sleep disruptions caused by sleep apnea could damage the nightly process of bone turnover. These consistent disruptions over time could lead to bone loss and the development of osteoporosis.
“If sleep disorders like obstructive sleep apnea affect bone metabolism, they may have diagnostic and therapeutic implications for many patients, including those affected by sleep apnea in their early, bone modeling years,” said lead author Dr. Christine Swanson.
Osteoporosis is only the latest ailment to be associated with sleep apnea. OSA has also been linked with heart disease, high cholesterol, diabetes, depression, obesity, high blood pressure, asthma, stroke, and cancer.