It's been 3 years since this thread was active, but I thought I'd chime in since I travel a lot. I totally get the struggle of wanting to leave your CPAP machine behind to save on baggage costs, but still wanting a good night's sleep while you're away. First off, if you're willing to shell out some extra cash, business class flights often have better amenities and more room to stretch out, so you might be able to sleep comfortably without your CPAP. Another option to consider is renting a CPAP machine at your destination. Some places even offer a rental service where they'll deliver the machine to your hotel room. It might be a little pricey, but could be worth it for a good night's sleep.