(For Sleepy Mommy703) I was prone to sinus infections when I was younger, however if you clean your mask daily, and tube every other day it shouldn't happen. In fact keeping the system clean and tubes disinfected using some basic tools out there (sprays or baby shampoo) should help with the onset of sinus infections. If you skip more than 1 day, you risk about 24 billions extra germs and bacteria entering your sinus cavity (way more than a normal day out in the park). Remember also that if you have the humidifier on, and the temp set below your room temperature, it is best to put the machine on the floor, as to avoid accumulation of water, which will breed bacteria in any part of the tube or mask. If you don't use a humidifier, you probably live in Florida or a nice humid zone, with that though comes the extra disinfection that should occur daily. You can purchase inexpensive cleaning supplies and filters which your lungs will appreciate.