Pramipexole and trouble sleeping

Hello,

My husband currently takes a low dose of pramipexole for his PLMD. Without it, he flails horribly. He has been sleeping badly lately. Sometimes he has trouble falling asleep. Sometimes, he gets up SUPER early and can't get back to sleep. His Dr recommended upping the dose, but this is certainly not a med he wants to keep upping. Plus, sleep issues appear to be a common side effect. Has anyone taken a supplement while taking this med that helps with sleep? Is it safe to maybe try Melatonin or Magnesium in addition?

Hi renrenbri.

This is really a question for his doctor or chemist/pharmacist.

I don't use Pramipexole yet, although I expect that I will have no choice eventually, but if I was using it I think I would try the Melatonin anyways unless the fine print on the meds precluded it.

If I was still in doubt I would ask my pharmacist. He probably knows more than my doctor about chemical combinations and his advice is free. :)

A quick check on line showed no interaction between pramipexole and melatonin. There is a moderate interaction between pramipexole and alcohol. See this link. I agree with BUG, in that the pharmacist is a good source of information in addition to the doctor.

Yes, the doctors definitely don't offer advice on supplements. I know Magnesium helps me, and I would imagine it couldn't hurt his PLMD, but I worry that it would make the apnea worse. Perhaps it is worth a call to the pharmacist.