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Deepnap

Deepnap
Joined Aug 2022
Deepnap
Joined Aug 2022

Hi, Sierra, many thanks for your comments and the links.

I could share a password-protected zip file of the entire dataset (165 MB) via tranfernow.net or similar platform that does not require registration. The data set does not seem to include my identity. If you agree, I could send you a link to the file (if this is allowed here) and the password.

I seem to be seeing some interesting patterns in the data.

The big rises in AHI seem to appear right after sleep onset and towards the end of the night. The overview daily screenshot below shows my 3 travels to the toilet and right after that, when I go back to sleep, the AHI rise is clearly seen.

The other screenshot shows the last big rise of AHI around 6pm after my visit to the toilet. What is interesting there is that right after the end of the 5 min ramp period set in the CPAP machine, the expiration rate frequently drops to zero. This pattern seems to be repeating across the entire data set. Maybe I should remove the ramp setting entirely. Also, my expiration rate always is lower then the inhalation rate. Is this normal?

Initially, a polygraph at home put me at an AHI of 37, the first night in the sleep lab came up with AHI=25, after that, 2 nights in the lab were used to determine a pressure of 9 for me. Apparently, at this stage, we talked about 1/3 of apneas being central. When I went back to the lab after wearing CPAP for about 6 weeks, the pressure settimg was reduced to 7 recognizing that central appneas were predominant. Since then I have played a little with the pressure; it is set to 7 now.

I have done a 36h ECG which found nothing except that my heart rate at night is around 50, that is why drugs that further reduce the heart rate are not conisdered at the moment. I will have a head MRI in 2 weeks looking if there are any blood flow issues in the brain. Thyroid is normal so are static ECG and heart ultra sound inspection. Currently I am wearing a 24h blood pressure monitor.

My current hypothesis is that I may have a too low arousal threshold as mentioned in the paper: Breathing Re-Education and Phenotypes of Sleep Apnea: A Review J. of Clinical Medicine P. McKeown et al. 2021