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Sierra

Sierra
Joined Jul 2018
Bio

CPAP: AirSense 10 AutoSet

Set to CPAP Fixed Mode

Pressure 11 cm

Ramp: Auto

Ramp Start: 9 cm

EPR: 2, Full Time

Mask: ResMed AirFit P10 Nasal Pillow

Canada

Sierra
Joined Jul 2018
Bio

CPAP: AirSense 10 AutoSet

Set to CPAP Fixed Mode

Pressure 11 cm

Ramp: Auto

Ramp Start: 9 cm

EPR: 2, Full Time

Mask: ResMed AirFit P10 Nasal Pillow

Canada

Is see that the company that makes this breathing simulator, IngMar Medical, makes 35 different standard patient models, but claim they can be easily tweaked based on specific needs. There is a Kussmaul Breathing pattern listed but not the specific Cheyne-Stokes Respiration. But they provide a link to contact them for specific requests.

The ResMed AirSense 10 does detect and report CSR, but it is not always accurate. Have a look at this thread which shows some sleep reports from an AirSense 10 reporting CSR (areas highlighted in green). I believe a standard CSR is waxing and waning breathing effort with central apnea events between them. The events reported in this thread do not have the smooth waxing and waning, and also have obstructive events between each cycle instead of central events. To me a true CSR pattern is a sine wave of smooth breathing effort with CA events between more of them. In other words breathing effort is reduced until there is no flow, and there is no obstruction.

The Phillips DreamStation machines report Periodic Breathing instead of specifying it as CSR. I'm guessing that the reason is that their detection method is really not specific enough to be sure it is CSR. ResMed are reporting it, but perhaps not always correctly.

I am a mechanical engineer, and not a medical professional, but CSR would seem to be easy to simulate. You would just use a slow sine wave function to drive breathing effort. The speed of the wave and time between waves would need to be about 12 seconds or so to allow the apnea machine time to identify a central apnea event. Here is an example from my personal sleep reports of what I believe a true CSR event looks like. In this case the ResMed has identified it correctly as CSR.

Hope that helps some,

On falling asleep one of the very minor things I do is set my machine to warm up. I then starts heating up the humidifier reservoir. It is a menu item on the User menu. I also try to avoid napping during the day to build up sleep demand, and also try to avoid averaging more than 7-8 hours a night sleep, with 7.5 being about ideal for me.

On the event that woke you up, it looks like a standard obstructive apnea and was preceded by a hypopnea event. Your Flow Limitation was not all that high at the time. Your machine responded with an increase in pressure, but of course by the time the event happens it is too late to prevent it. That is a good illustration of why a higher minimum pressure is helpful. Perhaps if you minimum was set at 16 cm, the event would have been avoided. But it is a little early for that conclusion yet.

Not sure what is happening with the respiratory rate being clipped. Perhaps the A10 does not report anything higher than 50, or OSCAR has a bug in reporting it. The real concern is that you are having the Tachypnea type breathing which is rapid and shallow. Notice that your tidal volume goes down when the breathing rate goes up. Definitely something to discuss with your doctor. The good news is that it is about the only abnormality left on your sleep report. It may be possible that use of EPR full time could reduce this type of breathing, but it is a bit early to try that. If things settle out with these low AHI numbers, you may want to try EPR at 1 cm to see if that helps, and then 2 cm. I only use 2 cm, but it seems to help me a lot in reducing hypopnea.

If these low AHI numbers hold up with more nights like this, it would appear there is no justification for a BiPAP machine. If you add back the EPR, pressure may need to be increased some, but probably not as high as 20.

The time thing I believe is a design problem with the ResMed AirSense machines. I have found you can advance the time, but you can't set it back. Right now I am running 1 hour ahead, because I can't set it back. I have researched it a few times, and if you find a solution let me know. But, I think the only way may be to do a full factory reset, which means you lose all your data stored in the machine, and you have to do a full set up of all your pressure settings etc... While you will not lose your data that is stored in OSCAR you will lose whatever is in the machine memory. I have never thought it was worth it, so I live with the time error. ResMed have released an AirSense 11 machine, and I would hope they would have fixed this time issue. There should be an easy way to switch between daylight savings and standard time, or even do it automatically. They are way behind the time on this issue!

Well, that is looking more encouraging! I see your pressure increased slightly and seems to be mainly driven by Flow Limitations. The rapid frequency of OA events is gone, and that is good news, but one night does not prove much yet. The collar may be helping. More nights and time will tell. Yes, most people are more prone to obstructive events when sleeping on their back. I do not try to avoid sleeping on my back, but I have back issues and my back certainly encourages me to sleep on my side more. Some people go to the extreme of sewing a tennis ball into the middle of the back of their PJ's. It sounds cruel to me, but that probably would encourage sleeping on a side rather than their back! I recall from my sleep study that the apnea frequency was slightly higher when sleeping in the back position.

I noticed that your start pressure on the ramp has gone back to 5 cm. If you find that more comfortable that is fine, but most, and especially when there is flow limitation issues, find a higher pressure like 7 to 9 cm can make breathing easier. What I do is take really quick deep breaths and see if I can feel any flow restriction. I increase the start pressure until I can't feel any restriction at all to the quick deep breaths. In my case I found 9 cm to be just right. I don't like that feeling that the machine or mask is restricting the flow of air into my lungs. Kind of gives me a suffocating feeling. The other thing you can do for comfort is set the EPR to 3 cm, but also set it to Ramp Only. Then you will get the help exhaling with the EPR exhale pressure reduction up until the time you go to sleep. Then it will turn off.

Your main AHI score for this night is coming from hypopnea. EPR full time may help that, but I would not try that until you have established a baseline with the machine in Auto, and with the cervical collar.

On the Leak Rate graph I find it helpful to set the leak rate red line. To do that you mouse over the Y-Axis scale and right click to bring p the options, and then click on Dotted Lines. Then check off the Leak Rate Upper Threshold box. That will display the red line on the graph. I don't worry much about the leak rate as long as it is under that line. Under these options I also set the Y Axis to Override with a min of 0 and max of 50. This keeps the relative proportions the same from day to day. Auto Scaling can make things look worse than they really are.

I had a closer look at your OSCAR data and have done a little bit more google research. The first thing I need to say is that I am a retired mechanical engineer and not any kind of medical professional. I draw my experience from reviewing my and my wife's data, and many others from this forum and others. With that context these are my thoughts, in no particular order.

That period of time where you had the very high respiratory rate is likely called Tachypnea or Nocturnal Tachypnea if you were asleep when it happened. It seems to be fairly rare but has been seen in people being treated with a CPAP. Possibly it happens in others, but without a CPAP or titration test equipment, it is never recorded. You can google it, but I am not sure in your case that it has an obvious cause. If you were awake, it could be simple anxiety, and I am not sure one can get anxious when asleep. If it is anxiety there are a number of drugs that can be used, but one should question if they should be used. I have taken an Ativan single pill before cataract surgery to deal with anxiety, but I think using it on an ongoing basis can be addictive. You mentioned Ambien, and that would likely be less addictive, but may have other side effects. I take a beta blocker, bisoprolol, for blood pressure control, but I understand it can be used, off label, to control anxiety as well. If you feel it is anxiety these are things to discuss with your doctor.

The areas flagged by your CPAP as CSR or Cheyne-Stokes Respiration, are more of a concern. I suspect those are quite disruptive to your sleep, and they may be resulting in low blood oxygen levels. You could consider getting an oximeter that clamps on your finger and gives a record of O2 levels during the night. SleepyHead and I believe OSCAR can accept the data from some of these meters so you can correlate events like the CSR flagged times to O2 levels. I believe OSCAR should give you some information on which meters it can accept data from.

With respect to it actually being true Cheyne-Stokes Respiration I am not so sure. Have a look at this simplified illustration comparing CSR to another condition called Biot's. True CSR has a smooth waxing and waning pattern, while Biot's does not. I do not see that in your example. It is more of a sudden increase and then some waning back to nothing.

Here is an example of what I think is true CSR from my personal data back in 2018 when I was having issues with it and central apnea.

Notice the smooth waxing and waning which starts even before the CSR green areas. The other big difference is that you are having obstructive apnea events between each while I am having central apnea events, which is no obstruction, just me not wanting to breath. I don't know much about Biot's other than it is rare, and your pattern does not fit it exactly either. Not sure if it is associated with OA or CA events. I think there is a good possibility that what you have is simply obstructive events with gasping periods for air between each one, and not Biot's either. That would be very disturbing to your sleep.

So this all said, I think for the short term, I would focus on more pressure in auto mode to see if the obstructive events can be prevented with more pressure. If my theory about you gasping for air between each obstruction should stop too, if the obstruction is prevented.

The part about doctors is complicated. I am in Canada and I am sure the overall system is different here. I have just gone to a sleep clinic where they give you a home test kit to take home. They send the results out to some cyber doctor somewhere that is supposed to be qualified to read them. Then they want you to buy a machine for $2400. Since I have no insurance for CPAP, I just bought my machine on line for about $800 and have done everything myself since then.

If you are in a situation where your insurance will cover it, I would try to find a pulmonologist that has sleep apnea experience and show them the results you are getting. If increased pressure does not solve things you need to get to the bottom of what is happening. At some point you may need to get a cardiologist involved too.

But for now give the 15/20 auto pressure setting a try. If it helps but still jams out at 20 cm, then you probably will have to pursue the BiPAP alternative with the hope a bit more than 20 will help. They go up to 25 cm. The extra pressure support from the BiPAP is not looking promising as you did not get a significant improvement with the EPR at 3 cm.

Your test in Auto at 15 min and 20 max should be very informative as to what possibilities there are. The cervical collar is still worth trying too. It may provide relief from the rapid sequencing of obstructive events.