That looks pretty good. I would suggest one more layout change. Slide the bar up on the right so the Pressure, Mask Pressure, Flow Rate, Minute Vent., Flow Limit., and Leak Rate show on the screen. You can change the order by left clicking on the title of the graph and then drag it up or down. Clicking and dragging on the gray dividing lines between the graphs can make individual graphs bigger or smaller.
From what I can see your leaks are fine, and your pressures are not all that high. Your obstructive apnea is low, suggesting you do not need more pressure. Your central apnea index is very high though, which suggests less pressure is needed. The machine as it is set up is not behaving much different than a AirSense 10 AutoSet with EPR turned on. The only difference is that your pressure support is 4 cm and the maximum EPR on an AutoSet is 3 cm. Pressure support and EPR are both simply the difference between inhale pressure (IPAP) and exhale pressure (EPAP).
Are you planning to try to adjust and improve the setup yourself, or are you going to ask the clinic to adjust it for you. My initial thought if you were going to adjust it yourself would be to set the pressure support to zero. That alone may help quite a bit. Central apnea often can be aggravated by higher pressure. Reducing pressure support should reduce pressure. If that helps but is not enough to bring down the centrals to an acceptable level, then I would next start to reduce the Maximum IPAP. While making these changes you will want to watch the obstructive apnea index. Reducing pressure support should not hurt it. But reducing IPAP may eventually cause it to come up, and there can be a trade off point where reduced centrals are being offset with increased obstructives.
If you are going to make these changes yourself here is a video on how to get into the clinical menu to do it. It is for an AirSense, but the AirCurve should be very similar. The menu choices will be slightly different. The only setting you would want to change initially would be Pressure Support, and then perhaps later Max IPAP if necessary.
If you are going to have a clinic do it, I would just ask if you can try no pressure support, and if that does not help, then reduced IPAP.
If you can post this same graph with the graphs I listed above showing, I can give you a better idea as to what the IPAP may have to be reduced to. While my AHI were not as high as yours, I live at 2000 feet, and I have had central apnea issues. I was able to improve AHI a lot by turning off EPR which is essentially the same as PS, and by reducing pressures, in my case from a maximum of 15 cm to around 11 cm. I have a feeling you may be able to reduce pressures down into the 8-9 cm range. But, the proof is always in the pudding. One has to try it to see what it actually does.