We use cookies and other tools to enhance your experience on our website and to analyze our web traffic.
For more information about these cookies and the data collected, please refer to our Privacy Policy.

Sierra

Sierra
Joined Jul 2018
Bio

CPAP: AirSense 10 AutoSet

Set to CPAP Fixed Mode

Pressure 11 cm

Ramp: Auto

Ramp Start: 9 cm

EPR: 2, Full Time

Mask: ResMed AirFit P10 Nasal Pillow

Canada

Sierra
Joined Jul 2018
Bio

CPAP: AirSense 10 AutoSet

Set to CPAP Fixed Mode

Pressure 11 cm

Ramp: Auto

Ramp Start: 9 cm

EPR: 2, Full Time

Mask: ResMed AirFit P10 Nasal Pillow

Canada

I have been trying to think how you could get titrated to a fixed pressure of 5 cm, and now you are getting higher AHI including both OA and CA events. Getting CA events if you are sensitive to pressure is not unexpected. However getting more OA events with pressure is unusual. About the only way I can think of to explain your outcome requires the assumption of two causes. One is that during your titration test, the technician quickly observed that you are sensitive to pressure causing CA events, and as a result limited pressure to 5 cm, so your titration outcomes are based on that very low pressure. Now you are using the AutoSet machine with the maximum pressure set at the machine maximum of 20 cm. It is responding to snore which does not seem to be an issue, flow limitations which you have a few of, and of course to obstructive apnea, which seems to compound the problem by creating both central apnea and obstructive apnea. There is a condition which some may describe as mixed or complex apnea where you have a respiratory control system instability. In SleepyHead that can show up as an oscillation of the Minute Ventilation rate. It creates a waxing and waning breathing effort effect. Sometimes at the minimum of the breathing effort this is identified as a central apnea event by your machine. And other times it may result in an obstruction and is flagged as a OA event. However the cause is really the same -- the breathing control system instability. And the control instability can be made worse with higher pressure and pressure support or EPR.

Here is a SleepyHead screen from a couple of nights ago where I observed something like that. What you can see is that up until 6:34 I was sleeping well, with a uniform regular breathing pattern, and very stable Minute Ventilation. Then something happens. The machine did not flag it, but you can see from the Mask Pressure graph it started to test it with the 4 Hz pressure cycle. The band that paints is fairly wide indicating an obstruction, but it does not last long enough to get flagged. However this starts the control instability cycle, like a car on cruise control encountering a hill. The waxing and waning starts and the Minute Ventilation starts to cycle. Part way through the waning part the airway closes and is flagged as a OA event. Wide mask pressure band painted. The next cycle ends in a CA event. Notice that the mask pressure band painted is not as wide. Then this continues with the next two cycles ending in an OA event, one in nothing, and then one more as a CA event. So that is my understanding of what mixed apnea may be. The control system instability creates both obstructive and central events. So that may be what is happening in your case. If you look at the zoomed in view of the areas where you are getting a mix of events you may see a pattern like this.

In any case I hope that helps some. It is about the best explanation I can come up with. I am guessing but I think with the APAP machine you now have the solution may be to really reduce pressure to the point where the respiratory control system is stable, and at the same time, hope that pressure is enough to resolve the obstructive apnea.

Welcome to the forum. I actually had an experience using my AirSense 10 AutoSet somewhat similar to yours. The cause may not be the same, but just in case, I will explain. I woke up in the night thinking that there was a fire in the house because I could smell smoke. However, there was no smoke alarm, so I convinced myself to go back to sleep. But it seemed to get worse so I even reached over to feel the machine to see if the machine was overheating or was on fire. It felt fine, so I finally got up to see what the heck was going on. What I discovered was that I had forgotten to fill my humidifier, and it had run out of water and boiled dry. The heat combined with some residual minerals etc in the bottom of the reservoir was making the stink. It was not unlike the smell from a bag of well used sports equipment. The solution was easy. Clean the reservoir and fill with clean water.

If that is not your problem, then I would suggest a thorough cleaning of your equipment if it really picked up smoke from the house. I would use full strength vinegar with a bit of a soak. This is what I use to clean my water reservoir and equipment. In your case I would follow that with a solution of baking soda and water to deodorize. Then a wash with Dawn liquid dish detergent and water, and finally a rinse with water. Hang up to drain and dry. With a thorough cleaning there should be no smell or health risk. If the issue is smoke from the house, you may want to change the air filter on the machine (located on left side). There may be some smoke smell trapped there.

That certainly is a bit puzzling considering that your titration prescription was 5 cm fixed with 2 EPR. My observations are that the majority of your central apnea which is the most significant component is occurring at the higher pressures. That is not unexpected. However, it seems a bit odd that you are also getting obstructive apnea at those higher pressures. Just looking at your graphs, is it possible you were awake from 4:30 to 5:45? There is an absence of events during that time, and your respiration rates seems high.

I am not a sleep technologist, just another CPAP user, that his issues with mixed obstructive and central apnea. Not sure if you are comfortable with adjusting your machine, and if not then ask your supplier to consider it. That said, if it were my machine I would put a limit on the maximum pressure to see if it helps reduce the central apnea events. I would also turn the EPR off. It often makes central apnea worse. If you can't make any progress with it turned off, then it may be worth trying it again. But for now I would turn it off. It makes the pressure on inhale run higher, and at this point, I think you want to limit pressure. So, my thoughts would be to leave the minimum at 5 cm and set the maximum at 10 cm, and turn EPR off to see if that improves things.

The other thing that would be interesting would be to zoom in on that cluster of events that starts at about 6:00. You can do that by left clicking on the area repeatedly until you can see the individual breaths of air. It could be revealing as to the type of central apnea you are having. Post what you get when zoomed in.

Hope that helps some.